interleukin 34


IL34 (may also be known as: None)




Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]


si:ch211-239j19.3 Danio rerio
Il34 Mus musculus
Il34 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2458 hypothetical protein LOC146433 decreases with age Molecular mesenchymal stem cell Human IL34 27.7% Decrease DNA Methylation
DAA2409 interleukin 34 decreases with age Molecular dermis Human IL34 17.6% Decrease DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0006954 inflammatory response biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0045087 innate immune response biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0005157 macrophage colony-stimulating factor receptor binding molecular_function
GO:0008083 growth factor activity molecular_function