homeobox B1


HOXB1 (may also be known as: None)




This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008]


lab Drosophila melanogaster
hoxb1a Danio rerio
Hoxb1 Mus musculus
Hoxb1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2403 homeo box B1 decreases with age Molecular dermis Human HOXB1 15.6% Decrease DNA Methylation
DAA2452 homeo box B1 decreases with age Molecular mesenchymal stem cell Human HOXB1 49.3% Decrease DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007389 pattern specification process biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0021570 rhombomere 4 development biological_process
GO:0021571 rhombomere 5 development biological_process
GO:0021612 facial nerve structural organization biological_process
GO:0021754 facial nucleus development biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0048646 anatomical structure formation involved in morphogenesis biological_process
GO:0048704 embryonic skeletal system morphogenesis biological_process
GO:0005634 nucleus cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003677 DNA binding molecular_function
GO:0003700 sequence-specific DNA binding transcription factor activity molecular_function
GO:0019904 protein domain specific binding molecular_function
GO:0043565 sequence-specific DNA binding molecular_function