microfibrillar associated protein 5


MFAP5 (may also be known as: None)




This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2. [provided by RefSeq, Jul 2008]


Mfap5 Mus musculus
Mfap5 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2400 microfibrillar associated protein 5 decreases with age Molecular dermis Human MFAP5 15.0% Decrease DNA Methylation
DAA2449 microfibrillar associated protein 5 decreases with age Molecular mesenchymal stem cell Human MFAP5 46.4% Decrease DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0001527 microfibril cellular_component
GO:0005576 extracellular region cellular_component
GO:0005578 proteinaceous extracellular matrix cellular_component
GO:0005201 extracellular matrix structural constituent molecular_function