capping protein (actin filament), gelsolin-like


CAPG (may also be known as: None)




This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]


si:ch211-114c12.4 Danio rerio
Capg Mus musculus
Capg Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2411 gelsolin-like capping protein decreases with age Molecular dermis Human CAPG 20.1% Decrease DNA Methylation
DAA2460 gelsolin-like capping protein decreases with age Molecular mesenchymal stem cell Human CAPG 19.3% Decrease DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0006461 protein complex assembly biological_process
GO:0030031 cell projection assembly biological_process
GO:0051016 barbed-end actin filament capping biological_process
GO:0005634 nucleus cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0008290 F-actin capping protein complex cellular_component
GO:0031965 nuclear membrane cellular_component
GO:0042470 melanosome cellular_component
GO:0003779 actin binding molecular_function